Fig. 5.—

Expression conservation of miR-34 seed neighbors. The neighborhood of miRNA seeds was analyzed regarding expression changes in dauer and infective larvae. The neighborhood subnetwork of the mir-34 seed reveals conserved upregulation of all Pristionchus pacificus seed neighbors. Node color represents expression changes classified into upregulated (blue), downregulated (red), and unaffected (light gray). Barplot next to a node represents the number of times a miRNA seed was identified in a specific nematode. Note that mir-4933 of Caenorhabditis elegans was not measured in our data and is represented in the light gray pie.