Table 3.

Tumor-to-blood ratio in different tumor cells in in vitro study.

	1 hr	4 hr	24 hr	48 hr
L858R/blood	2.25 ± 0.001	3.75 ± 0.001	2.64 ± 0.000	3.98 ± 0.000*
E746-A750 del/blood	2.45 ± 0.000	2.96 ± 0.001	2.68 ± 0.000	5.55 ± 0.002*
Wild-type EGFR/blood	2.79 ± 0.001*	2.91 ± 0.000	1.22 ± 0.000	3.87 ± 0.001*
Vector/blood	1.79 ± 0.001	1.97 ± 0.000	2.37 ± 0.001	13.12 ± 0.000

Data shown as average ± standard deviation (n = 3 for each tumor pair). All other three cell lines were compared to L858R tumor cells at the same time point, and statistically significant difference (*P < 0.05) is indicated by an asterisk.