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The number of RGCs in the eyes treated weekly with 80 μg/kg/day aldosterone. (a) In the central retina, RGC was decreased 4 weeks after the administration of aldosterone. (b) In the peripheral retina, however, reduction in the number of RGCs was already detected at 2 weeks after the administration of aldosterone. Results are expressed as the mean±S.E.M. (n=4 in each week). #P<0.05, *P<0.001 versus control (Dunnett's multiple comparison test)
