Gene therapy |
Knockdown of proteins required for HIV replication. For example, CCR5 |
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Overexpression of restriction factors. For example, Human: Rhesus chimeric TRIM5a |
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Engineered T-cell receptors. For example, Third-generation chimeric antigen receptors |
Immune based |
Therapeutic vaccination |
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Cytokine therapy. For example, 1h7, IL15 |
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Anti-inflammatory agents |
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Growth hormone |
HIV reactivation |
HDAC inhibitors—For example, SAHA |
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TLR agonists |
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PKC activation |
Cytotoxic approaches |
Autologous stem-cell transplant |
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Allogeneic stem-cell transplant |