Table 1. Stemness-linked genes differentially expressed on whole genome microarray analysis (fold change >2.0, adjusted P<0.1) in the SK-N-BE(2)C DoxR and DoxR-v cell lines relative to their parental (WT) lines.
| Gene symbol | Gene Entrez ID | Gene name | DoxR/WT fold | DoxR-v/WT fold |
|---|---|---|---|---|
| ABCB1 | 5243 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 4.23 | 2.04 |
| ABCC4 | 10257 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 2.12 | NS |
| LMO2 | 4005 | LIM domain only 2 (rhombotin-like 1) | 4.07 | 2.28 |
| SOX2 | 6657 | SRY (sex determining region Y)-box 2 | 2.75 | NS |
| ERCC5 | 2073 | Excision repair cross-complementing rodent repair deficiency, complementation group | 2.12 | NS |
| S100A10 | 6281 | S100 calcium binding protein A10 | 13.1 | N.S. |
| IGFBP3 | 3486 | Insulin-like growth factor binding protein 3 | 4.55 | 1.84 |
| TCF3 | 6929 | Transcription factor 3 | 2.56 | 1.78 |
| VIM | 7431 | Vimentin | 24.3 | 5.19 |
NS, No significant fold change