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. 2013 Aug;183(2):422–430. doi: 10.1016/j.ajpath.2013.05.006

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© 2013 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

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DMA rescues pups from LPS-triggered spontaneous abortion in a dose-dependent fashion. The cumulative percentage of pups lost to spontaneous abortions over time is shown (A) and the corresponding Kaplan-Meier survival curves are shown (B). The effect of varying doses of DMA on the rate of pups delivered over time was determined (P < 0.0001, P < 0.0001, P < 0.0001, P < 0.0001, and P < 0.01, corresponding to highest to lowest dose, respectively). C: The dose-response relationship between DMA and the rescue of pups from spontaneous abortion.