TABLE 2.

Studies Examining Working Memory

Reference	Population, N, Design	Time Since Treatment	Treatment Regimen	Outcome	Limitations
Mabbott et al. (2008)	62 survivors of PF tumor; 10 non-CNS tumor control subjects; Cross-sectional	Mean since diagnosis: PF groups = 5.4 y; non-CNS group = 5.9 y	PF group: 31/62 received CRT; 31/62 received surgery only; Non-CNS group received chemo + surgery	No differences were found between PF CRT, PF Surgery, and non-CNS tumor groups on working memory.	Heterogeneity in type of treatment received; Unequal group sizes.
Spiegler et al. (2004)	34 survivors of pediatric posterior fossa tumor; Longitudinal.	Range (0–10 y)	Surgery + CRT: 10/34; Surgery, CRT, + chemo: 24/34	Working memory declined by 1.86 standard points per year; with worse declines just after treatment.	Heterogeneity in treatment received and complications; No control group; Missing data.

Note. PF = posterior fossa; CNS = central nervous system; Y = years; CRT = cranial radiation therapy; chemo = chemotherapy.