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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2012 Jun 28;21(9):1510–1519. doi: 10.1158/1055-9965.EPI-12-0320

Table 4.

Overall breast cancer rates per 1000 mammograms by comorbidity status and time to previous mammogram c (N=3316)

Overall 4–18 Months 19–30 months 31–42 months >42 months/first screening d
Rate (95% CI) p Rate (95% CI) p Rate (95% CI) p Rate (95%CI) p Rate (95% CI) p

All 6.9 (6.6,7.2) -- 6.1 (5.9,6.4) -- 8.1 (7.8, 8.9) -- 9.9 (8.5,11.6) -- 14.6 (13.4,15.9) --
No comorbidities 6.6 (5.8,7.5) Ref 5.7 (4.9, 6.6) Ref 8.0 (5.9,10.8) Ref 8.0 (4.7, 13.5) Ref 14.6 (10.4,20.4) Ref
Stable a comorbidities 6.7 (6.4,7.0) 0.821 6.0 (5.7, 6.4) 0.489 8.0 (7.1, 9.0) 0.76 9.9 (8.0, 12.1) 0.60 14.7 (12.4, 17.3) 0.814
Unstable b comorbidities 7.5 (7.0,8.1) 0.084 6.6 (6.1, 7.2) 0.086 8.3 (7.0, 10) 0.58 10.8 (8.3,14.2) 0.63 14.5 (11.6, 18.1) 0.481

Results adjusted for covariates (age, race/ethnicity/BCSC registry)

a

Stable comorbidities are defined as age-related conditions with no influence on predicted 5 year mortality. Examples include arthritis, osteoporosis, depression, diabetes, thyroid disorders, stable coronary artery disease, and peptic ulcer disease (Appendix 1).

b

Unstable comorbidities are defined as life threatening or difficult to control with less than 5 year predicted mortality. Examples include severe heart failure, end-stage pulmonary disease, end-stage liver disease, renal disease, and diabetes with complications (Appendix 1).

c

Mammography use was categorized according to type of examination and time between mammography examination. Time to prior mammogram was calculated using last mammogram before cancer diagnosis for women with a cancer diagnosis and a randomly selected mammogram for women with no cancer diagnosis.

d

>42 months or first screen is defined as a screening mammogram with no prior mammogram within 42 months.