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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Lancet Oncol. 2013 Apr 16;14(6):472–480. doi: 10.1016/S1470-2045(13)70095-0

Table 4.

Best response in patients with anaplastic large-cell lymphoma, inflammatory myofibroblastic tumour, or non-small-cell lung cancer, by accession number

Dose level (mg/m2 per dose) Part Measurable or evaluable disease Best response Cycle maximum response observed Total cycles
Anaplastic large-cell lymphoma (n=9)
Patient 37 165 A2 Measurable SD .. >30*
Patient 38 165 A2 Measurable CR 2 9
Patient 39 165 A2 Measurable CR 1 >28*
Patient 41 165 A2 Measurable CR 5 6
Patient 42 165 A2 Measurable CR 3 >23*
Patient 43 165 A2 Measurable CR 1 4
Patient 57 280 A2 Measurable CR 2 12
Patient 62 280 A2 Evaluable CR 2 >16*
Patient 78 280 A2 Measurable PR 1 >7*

Inflammatory myofibroblastic tumour (n=7)
Patient 4 100 A1 Measurable SD .. 24
Patient 45 165 A2 Measurable PR 1 >20*
Patient 48 280 A1 Measurable PR 5 >19*
Patient 69 280 A2 Measurable SD .. >14*
Patient 73 280 A2 Evaluable SD .. 5
Patient 74 280 A2 Measurable SD .. 3
Patient 75 280 A2 Measurable PR 3 >11*

Non-small-cell lung cancer (n=2)
Patient 30 165 A2 Measurable SD .. 5
Patient 36 165 A2 Measurable PR 3 16

SD=stable disease. CR=complete response. PR=partial response.

*

Patient still on protocol therapy.

Patient off treatment to receive bone marrow transplant.