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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Lab Invest. 2012 Oct 22;93(1):96–111. doi: 10.1038/labinvest.2012.148

Figure 7. Macrophage infiltration at the ulcerated site in control and PC-iShhKO mice.

Figure 7

Stomachs sections were collected from (A, B) control and (C, D) PC-iShhKO mice 2 days after ulcer induction and immunostained for myeloid cell marker F4/80. Representative figures of n = 6–8 mice per group. Images were captured at 20X magnification. Higher magnification images shown in B and D were captured at 40X magnification. Scale bars = 150 microns. The number of F4/80 positive cells were counted and expressed as the mean + SEM cells/high power field (shown in parentheses). *P<0.05 compared to controls, n = 6–8 mice/group. (E) Quantification of gastric CD11bhighF4/80high cells in control and PC-iShhKO mouse stomachs. (F) MIP-1α tissue concentrations measured in control and PC-iShhKO mouse stomachs. N = 5–6 mice per group, *P < 0.05 compared to PBS controls.