Fig. 2.

Schematic diagram of the SECIS element in the 3′UTR of mRNA encoding human GPx1. Regions of short conserved sequences are indicated by bold face type. Shading indicates regions of deletions, as described in the text. Light shading indicates the extent of the distal stem and terminal loop deletion; dark shading indicates the extent of the 5′ stem and conserved sequence deletion The oval area of dark shading indicates a conserved sequence region deleted in both constructs. The total SECIS deletion construct removed the entire sequence.