. Author manuscript; available in PMC: 2013 Aug 1.

Published in final edited form as: Acta Biomater. 2012 Apr 3;8(7):2815–2823. doi: 10.1016/j.actbio.2012.03.042

Table 2.

Statistical analysis of immunohistological staining of primary synovium and revision pseudomembrane.

	CD68	HLA-DR/CD68	CD163/CD68	M1/M2
Primary Synovium	72.2 ±3.103	0.48 ±0.03	0.52 ±0.11	0.46 ±0.04
Revision Pseudomembrane	78.3 ±6.22	0.85 ±0.05	0.34 ±0.08	2.87 ± 0.54
P values		p<0.0001	p = 0.1148	p = 0.0008

The ratio of M1/CD68+ cells in the synovium was 0.48 ± 0.03, compared to the ratio of M1 to CD68+ cells in the pseudomembrane of 0.85 ± 0.05 with p < 0.0001. There is a slightly higher proportion of M2 macrophages in the synovium (0.52 ± 0.11) compared to the revision tissues (0.34 ± 0.08) (p = 0.115). For the synovium the average M1/M2 ratio was 0.46 ± 0.04; this was compared to that of the pseudomembranes, which was 2.87 ± 0.54, with p = 0.0008 using an unpaired t-test.