Table 3.
Association of microbial biomarkers with respiratory symptoms and allergic sensitization at school age, in dual exposure (GNB + GPB) models
| Current Asthma*† POR (95% CI) |
Recurrent Wheeze* POR (95% CI) |
Allergic Sensitization*‡ PR (95% CI) |
|
|---|---|---|---|
| Family Room | |||
| Endotoxin (LAL) (> Median) |
0.4 (0.2 to 0.8)§ | 0.4 (0.2 to 0.97)§ | 0.8 (0.6 to 0.97)§ |
| Muramic Acid (> Median) |
0.7 (0.3 to 1.5) | 0.8 (0.3 to 1.7) | 1.0 (0.8 to 1.2) |
| Bed | |||
| Endotoxin (LAL) (> Median) |
0.8 (0.3 to 1.8) | 0.5 (0.2 to 1.1) | 1.03 (0.82 to 1.31) |
| Muramic Acid (> Median) |
0.4 (0.2 to 1.0) | 0.6 (0.3 to 1.5) | 1.06 (0.81 to 1.39) |
Adjusted for age, race, sex
Adjusted for maternal asthma
Adjusted for sex, race
p< 0.05
POR= prevalence odds ratio; PR = Prevalence ratio