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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Expert Opin Biol Ther. 2012 Jul 31;12(10):1383–1397. doi: 10.1517/14712598.2012.707184

Figure 3. The presence of Tr1-like cells at tumor sites and in the peripheral circulation of patients with cancer.

Figure 3

A. Expression of CD4+ T cells co-expressing CD132 and TGF-β infiltrating human HNSCC. A frozen tumor section stained with mAbs to CD4; CD132 and TGF-β and examined in a fluorescence microscope. Mag × 600. B. Flow cytometry data (reproduced with permission from ref. 57 by Bergmann et al.) for expression of CD132, TGF-β, IL-10 and IL-4 in CD3+CD4+ lymphocytes in PBMC or TIL of a representative HNSCC patient.