Table 2.

Effect of methanolic extract of A. spinosus (MEAS) on blood glucose level in diabetic rats.

Groups	Treatment	Blood glucose level (mg/dl)
		0 day	1st day	10th day	15th day
I	Control	86.75 ± 2.18	87.44 ± 2.34	62.66 ± 5.6	84.98 ± 3.8
II	Diabetic control (DC)	316.84 ± 47.13	354.74 ± 39.98	378.94 ± 7.05	342.83 ± 40.06
III	DC + MEAS 200 mg/kg	259.7 ± 27.9	221.1 ± 41.9a	108.4 ± 7c	89.84 ± 9.01c
IV	DC + MEAS 400 mg/kg	248.6 ± 31.4	138.3 ± 4.7c	95.7 ± 4c	81.26 ± 6.86c
V	DC + glibenclamide (10 mg/kg)	271.7 ± 33.1	185.2 ± 14.9b	86.6 ± 5.6c	72.16 ± 7.48c

The data are expressed in mean ± SEM. n = 6 in each group.

^ap < 0.05.

^bp < 0.01.

^cp < 0.001 compared with corresponding value of diabetic control animals.