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. 2010 Jul 25;18(4):217–224. doi: 10.1016/j.jsps.2010.07.003

Table 1.

The effect of cholesterol molar ratio and charge inducers on the encapsulation efficiency of fluconazole into multilamellar liposomes.

Liposome composition (molar ratio) Charge Encapsulation efficiency (% ±S.D.)
Phosphatidylcholine Neutral 23.104 ± 0.197
Phosphatidylcholine:cholesterol (1:0.6) Neutral 44.675 ± 0.324
Phosphatidylcholine:cholesterol:stearylamine (1:0.6:0.1) Positive 52.657 ± 0.231
Phosphatidylcholine:cholesterol:dicetyl phosphate (1:0.6:0.1) Negative 38.877 ± 0.164
Phosphatidylcholine:cholesterol (1:0.8) Neutral 50.236 ± 0.335
Phosphatidylcholine:cholesterol:stearylamine (1:0.8:0.1) Positive 59.998 ± 0.194
Phosphatidylcholine:cholesterol:dicetyl phosphate(1:0.8:0.1) Negative 43.533 ± 0.244