Proposed protective mechanism by PLC against DOX-induced cardiomyopathy. CT, carnitin acyl-carnitine translocase; CAT, carnitine acetyl transferase; CPT I, outer carnitine palmitoyltransferase; CPT II, inner carnitine palmitoyltransferase; PCC, propionyl-CoA carboxylase; ADR, adriamycin (trade name of DOX); (−) and (+) indicate inhibition and stimulation, respectively.
(Cited from Sayed-Ahmed et al., 2000a.)