Table 1.
Composition (mgs) of the prepared formulations |
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F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | |
MCP | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 |
HPMC | 90 | 70 | 90 | 30 | 90 | 70 | 70 | 80 | 90 | 80 | 70 | 80 |
CMC | 50 | – | 30 | 90 | 30 | 30 | 50 | 30 | 30 | 30 | 30 | 30 |
SSG | – | – | – | – | 20 | 20 | 20 | 30 | 10 | 30 | 40 | 30 |
Avecil | 30 | 50 | 50 | 50 | 30 | 50 | 30 | 30 | 40 | 30 | 30 | 30 |
Mag stearate | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
EC | – | 50 | – | – | – | – | – | – | – | – | – | – |
Methoda | DC | DC | DC | DC | DC | DC | DC | DC | DC | DG | DG | PS |
Tablet weight (mg) | 202 | 202 | 202 | 202 | 202 | 202 | 202 | 202 | 202 | 202 | 202 | – |
DC, DG, PS designate direct compression, dry granulation and pelletization spheronization, respectively.