Table 1.
Characteristics of 8607 stage IC-IV ovarian cancer patients in SEER-Medicare diagnosed between 1991 and 2005, stratified by occurrence of bowel obstruction.
| Overall n=8607 | No Obstruction n=7089 | Obstruction n=1518 | Time- to- event p-value | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| No. | (%) | No. | (%) | No. | (%) | ||
| Patient characteristics | |||||||
| Age at Diagnosis | <0.001 | ||||||
| 65 to 70 | 1655 | (19.2) | 1227 | (17.3) | 428 | (28.2) | |
| 70 to 74 | 2219 | (25.8) | 1708 | (24.1) | 511 | (33.7) | |
| 75 to 79 | 2176 | (25.3) | 1823 | (25.7) | 353 | (23.3) | |
| 80 and up | 2557 | (29.7) | 2331 | (32.9) | 226 | (14.9) | |
| Race | 0.923 | ||||||
| White | 7740 | (89.9) | 6350 | (89.6) | 1390 | (91.6) | |
| Black | 432 | (5.0) | 373 | (5.3) | 59 | (3.9) | |
| Other or unknown | 435 | (5.1) | 366 | (5.2) | 69 | (4.5) | |
| Marital Status | 0.021 | ||||||
| Married | 3619 | (42.0) | 2861 | (40.4) | 758 | (49.9) | |
| Unmarried | 4752 | (55.2) | 4018 | (56.7) | 734 | (48.4) | |
| Unknown | 236 | (2.7) | 210 | (3.0) | 26 | (1.7) | |
| Presenting Features | |||||||
| Year of Diagnosis | <0.001 | ||||||
| 1991 to 1995 | 2377 | (27.6) | 1853 | (26.1) | 524 | (34.5) | |
| 1996 to 2000 | 2479 | (28.8) | 2003 | (28.3) | 476 | (31.4) | |
| 2001 to 2005 | 3751 | (43.6) | 3233 | (45.6) | 518 | (34.1) | |
| Obstruction at diagnosis | <0.001 | ||||||
| No | 7815 | (90.8) | 6498 | (91.7) | 1317 | (86.8) | |
| Yes | 792 | (9.2) | 591 | (8.3) | 201 | (13.2) | |
| Comorbidity | 0.438 | ||||||
| Charlson index = 0 | 6957 | (80.8) | 5641 | (79.6) | 1316 | (86.7) | |
| Charlson index = 1 | 1001 | (11.6) | 867 | (12.2) | 134 | (8.8) | |
| Charlson index >= 2 | 649 | (7.5) | 581 | (8.2) | 68 | (4.5) | |
| Tumor Histology | <0.001 | ||||||
| Endometrioid | 600 | (7.0) | 492 | (6.9) | 108 | (7.1) | |
| Mucinous | 454 | (5.3) | 376 | (5.3) | 78 | (5.1) | |
| Other | 3331 | (38.7) | 2871 | (40.5) | 460 | (30.3) | |
| Serous | 4222 | (49.1) | 3350 | (47.3) | 872 | (57.4) | |
| Primary Tumor Resection | <0.001 | ||||||
| No | 2958 | (34.4) | 2714 | (38.3) | 244 | (16.1) | |
| Yes | 5649 | (65.6) | 4375 | (61.7) | 1274 | (83.9) | |
| Stage | <0.001 | ||||||
| 1C | 365 | (4.2) | 334 | (4.7) | 31 | (2.0) | |
| 2 | 693 | (8.1) | 614 | (8.7) | 79 | (5.2) | |
| 3 | 3893 | (45.2) | 3081 | (43.5) | 812 | (53.5) | |
| 4 | 3656 | (42.5) | 3060 | (43.2) | 596 | (39.3) | |
| Chemotherapy prior to obstruction | <0.001 | ||||||
| No | 5053 | (58.7) | 4373 | (61.7) | 680 | (44.8) | |
| Yes | 3554 | (41.3) | 2716 | (38.3) | 838 | (55.2) | |
| Tumor Grade | 0.009 | ||||||
| Well or moderately differentiated | 1458 | (16.9) | 1177 | (16.6) | 281 | (18.5) | |
| Poorly differentiated or anaplastic | 4143 | (48.1) | 3307 | (46.6) | 836 | (55.1 | |
| Unknown | 3006 | (34.9) | 2605 | (36.7) | 401 | (26.4) | |
| Ascites prior to obstruction | 0.191 | ||||||
| No | 5684 | (66.0) | 4629 | (65.3) | 1055 | (69.5) | |
| Yes | 2923 | (34.0) | 2460 | (34.7) | 463 | (30.5) | |