Table 2.
Multivariable Cox Proportional Hazard analysis of association between clinical and tumor characteristics in 8607 stage IC-IV ovarian cancer patients diagnosed in SEER-Medicare database between 1991 and 2005 and bowel obstruction.
| Adjusted Hazard Ratio | 95% CI | p | |
|---|---|---|---|
| Age at Diagnosis | <0.001 | ||
| 65 to 69 | Reference | ||
| 70 to 74 | 1.00 | 0.88 to 1.13 | |
| 75 to 79 | 0.80 | 0.69 to 0.92 | |
| ≥80 | 0.69 | 0.59 to 0.81 | |
| Year of Diagnosis | 0.001 | ||
| 1991 to 1995 | Reference | ||
| 1996 to 2000 | 0.84 | 0.74 to 0.95 | |
| 2001 to 2005 | 0.80 | 0.71 to 0.91 | |
| Stage | <0.001 | ||
| 1C | Reference | ||
| 2 | 1.76 | 1.16 to 2.68 | |
| 3 | 4.48 | 3.12 to 6.44 | |
| 4 | 4.82 | 3.35 to 6.95 | |
| Obstruction at diagnosis | <0.001 | ||
| No | Reference | ||
| Yes | 2.18 | 1.87 to 2.52 | |
| Tumor Histology | 0.002 | ||
| Serous | Reference | ||
| Mucinous | 1.45 | 1.14 to 1.83 | |
| Endometrioid | 0.89 | 0.72 to 1.08 | |
| Other | 1.13 | 1.01 to 1.27 |