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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 Feb 20;86(3):440–449. doi: 10.1016/j.ijrobp.2013.01.011

Table 1. New in vivo substrates of DNA-PKcs.

Protein Name Phosphorylation site Induced by References
Akt1/PKBα Thr-308
Ser-473
IR [117,118]
Hsp90α Thr-5
Thr-7
IR or apoptosis [96,97]
NR4A Ser-337 IR or camptothecin [95]
SAF-A/hnRNPU Ser-59 Calicheamicin or etoposide [98,99]
UPF1 Unknown Replication stress [140]
USF1 Ser-262 Insulin [141]