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. Author manuscript; available in PMC: 2014 May 7.
Published in final edited form as: Adv Mater. 2013 Mar 1;25(17):10.1002/adma.201204472. doi: 10.1002/adma.201204472

Figure 5.

Figure 5

Comparison of the in vivo growth of MCF-7 breast tumors induced by 2D and 3D pre-cultured cells under in vitro conditions. a, The same number of MCF-7 breast cancer cells pre-cultured by 2D and 3D methods were injected into the left and right armpits of the same athymic nude mice, respectively. (b,c) Typical tumors that grew for 10 days (b) and 20 days (c) after exoimplantation. (d) Average weights of tumors induced by MCF-7 breast cancer cells pre-cultured by 2D and 3D methods after having grown for 10 days and 20 days. “*”: p < 0.05, compared to 2D groups.