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. 2013 May 20;4(7):616–621. doi: 10.1021/ml400112h

Figure 4.

Figure 4

EP2 receptor activation induces macrophage activation. (A) P388D1 macrophages were pretreated with TG6-129 (10 μM) or vehicle for 1 h, then followed by incubation with EP2 selective agonist butaprost (10 μM) for 2 h. The mRNA levels of the indicated inflammatory mediators were measured by qRT-PCR. (B) EP2 mRNA levels in P388D1 macrophages stimulated with butaprost for 2 h (n = 3–4; ***P < 0.001; **P < 0.01; *P < 0.05, one-way ANOVA with post hoc Bonferroni test). Data are shown as mean ± SEM.