Table 6.
Stability of asparaginase at 4°C and at room temperature
| Time (hour) | % Difference from fresh prepared sample | |||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| 4°C | Room Temperature | |||||||
|
| ||||||||
| NHS | Asparaginase in BSA | NHS | Asparaginase in BSA | |||||
|
| ||||||||
| 0.10 IU/mL Low Control | 1.0 IU/mL High Control | 0.10 IU/mL Low Control | 1.0 IU/mL High Control | 0.10 IU/mL Low Control | 1.0 IU/mL High Control | 0.10 IU/mL Low Control | 1.0 IU/mL High Control | |
| 1.5 | 4.9 | 1.9 | 3.7 | -2.6 | 8.3 | -1.4 | 8.6 | 1.5 |
| 3 | -13.9 | -9.1 | 2.7 | -7.1 | -12.1 | -8.7 | 3.6 | -6.9 |
| 4.5 | -4.9 | -10.0 | 0.2 | -8.6 | 4.4 | -7.3 | 3.8 | -5.7 |
| 8 | 4.3 | -3.2 | 0.5 | -3.2 | 10.4 | -3.8 | 15.1 | -2.8 |
| 24 | 0.3 | -10.9 | -2.7 | -12.2 | 47.2 | -3.4 | -1.5 | -6.3 |
| 72 | -4.0 | -10.2 | -3.3 | -9.6 | 27.1 | -1.0 | -5.0 | -11.6 |
NHS: normal human serum.