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. 2013 Aug 1;9(8):e1003662. doi: 10.1371/journal.pgen.1003662

Figure 5. Patterns of diversifying and purifying selection in pipid AMP/HLP precursor proteins.

Figure 5

Site-specific mean posteriors of nonsynonymous (E(dN), black line) and synonymous (E(dS), grey line) codon substitution rates are plotted along an exemplary precursor protein sequence (prepro-CPF-St6). Sites for which the black plot line rises above grey one have dN/dS ratios >1 (suggesting diversifying selection); those for which the black plot stays below the grey have dN/dS ratios <1 (suggesting purifying selection). Sites showing significant evidence of diversifying or purifying selection (at Bayes factor >50) are labeled with ‘+’ and ‘−’, respectively.