Table 4. Activity of S. tropicalis peptides against a broad range of cell types.

	Gram-negative bacteria		Gram-positive bacteria		Eukaryote microorganisms		vertebrate cells
	E. coli	P. aeruginosa	S. aureus	M. luteus	S. cerevisiae	T. brucei	Erythrocytes	T-lymphocytes
Peptide	MIC (µM)	MIC (µM)	MIC (µM)	MIC (µM)	MIC (µM)	LC95 (µM)	HC50 (µM)	IC50 (µM)
CPF-St4	2–4	4–8	1	0,5	16	2–4	64	2
CPF-St5	1	4–8	1	0,5	16	1–2	64	8
CPF-St6	16	>256	>256	4	64	16–256	256	32–64
CPF-St7	128	>256	32	2	64	2–64	256	128
magainin-St1	64	>256	>256	32	128	8–>256	>256	>256
XPF-St4	32	128	>256	0,5	64	4	256	64
XPF-St5	1–2	8–16	16	1	32	2–4	128	8–16
XPF-St1	4	32	32–64	0,5	32	2–64	128	16
XPF-St6	2–4	16	8–16	0,5	8	2–4	64	8
XPF-St7	8	32	128	1	32	2–64	>256	16
XPF-St8	1	4	128	0,5	8	1–8	64	16
PFQa-St2	32	256	16	4	128	16–32	256	128
PGLa-St2	16	128	>256	2	64	16–32	>256	64

MIC, minimum inhibitory concentration, the lowest peptide concentration (in µM) in a series of twofold dilutions at which no growth was detected; LC₉₅, the lowest peptide concentration at which at east 95% of parasites was killed after 30 minutes; HC₅₀, the lowest peptide concentration causing at least 50% hemolysis; IC₅₀, the lowest peptide concentration causing at least 50% inhibition of Concanavalin A-induced T-cell proliferation. In case of variation among repetitive tests, observed minima and maxima for these values are given, respectively.