Table 1. GT-A fold glycosyltransferase families with deposited structures.
Family | Example enzyme | Stereo-specificity | Example Complex(es) |
GT-2 | SpsA | Inverting | UDP |
GT-6 | GTA | Retaining | UDP-Gal+Gal-Fuc |
GT-7 | GalT1 | Inverting | UDP-Gal, GlcNAc-GlcNAc |
GT-8 | LgtC | Retaining | UDP-Gal+Gal-Glc |
GT-13 | GnT1 | Inverting | UDP-GalNAc, UDP-Glc |
GT-15 | Kre2 | Retaining | GDP+Man+GlcNAc |
GT-27 | GNAc:Pep | Retaining | UDP+GlcNAc |
GT-43 | GlcAT-I | Inverting | UDP-GlcUA, UDP+Gal-Gal-Xyl |
GT-55 | MpgS | Retaining | GDP-Man |
GT-64 | Extl2 | Retaining | UDP-GalNAc |
GT-78 | MgS | Retaining | GDP |
GT-81 | ManT | Retaining | GDP |
Bold underlined families were assessed to have unambiguous whole acceptor and donor molecule electron density for analysis; those in italics have donor density.