Table 4. Genes identified as potential interesting using gene profiling in both VHS and STHS compared to spleen.
Gene name | qPCR:Adj p-values VHS vs Spleen | qPCR:Adj p-values STHS vs Spleen | qPCR:Up/Down regulated versus spleen | Spleen versus VHS resp STHS; Fold Change |
PPBP | 7.6×10−8 | 7.23×10−9 | DOWN | −360×, −1008× |
GTSF1 | 2.9×10−4 | 5.25×10−5 | UP | 1000×, 1000× |
Spi-C | 2.0×10−3 | 2.4×10−4 | DOWN | −12×, −51× |
VCAM1 | 0.011478 | 1.1 10−4 | DOWN | −10×, −6× |
ENPEP | 8.4×10−4 | 2.0×10−8 | DOWN | −324×, −1472× |
LUM | 3.4×10−3 | 5.43×10−7 | UP | 88×, 48× |
ITGAD(CD11d) | 8.5×10−3 | 1.6×10−3 | DOWN | −4×, −253× |
Col3a1 | 7.0×10−3 | 0.010 | UP | 23×, 18× |
Thy1 (CD90) | 0.024 | 4.19E-05 | UP | 3×, 6× |
PPBP: Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7), GTSF1: Gametocyte specific factor 1, SPI-C: Spi-C transcription factor, VCAM1: Vascular cell adhesion molecule 1, ENPEP: Glutamyl aminopeptidase (aminopeptidase A), LUM: Lumican, ITGAD: Integrin, alpha D, Col3A1: Collagen, type III, alpha 1, Thy-1 (CD90): Thy-1 cell surface antigen.