Table 2.
Number and percentage of subjects with plasma 25(OH)D concentrations above or below defined sufficiency cut-points at six-month follow-up, CaD v MAP pilot trial, n=85
| Treatment group | Deficient <37.5 (nmol/L) n (%) | Insufficient 37.5 to <75 (nmol/L) n (%) | Sufficient ≥75 (nmol/L) n (%) |
|---|---|---|---|
| Placebo (n=21) | 6 (28.6) | 15 (71.4) | 0.0 |
| Calcium1 (n=21) | 5 (23.8) | 11 (52.4) | 5 (23.8) |
| Vitamin D2 (n=22) | 1 (4.6) | 7 (31.8) | 14 (63.6) |
| Calcium + Vitamin D3 (n=21) | 1 (4.8) | 12 (57.1) | 8 (38.1) |
| P 4 | 0.09 | 0.41 | 0.10 |
1
Calcium: 2,000 mg elemental calcium daily given as 1.25 g calcium carbonate twice daily with meals
2
Vitamin D: 800 IU vitamin D3 given as 400 IU twice daily with meals
3
Calcium plus vitamin D as in footnotes 1 and 2 given together
4
Fisher's exact test for difference across treatment group within strata of vitamin D status; overall chi-square test for treatment group by status =p<0.001