Table 3.

Adjusted Changes in WOMAC Scores According to Number of “Worse” Joints^*

	Change in WOMAC Total† Mean (SD)	Change in WOMAC Pain† Mean (SD)	Change in WOMAC Function† Mean (SD)
Knee Global Assessment of Change
0	−3.02 (15.1)	−1.04 (3.9)	−1.40 (10.3)
1	0.69 (18.9)	0.48 (4.6)	0.15 (12.6)
2	4.62 (16.6)	1.21 (4.4)	3.02 (11.3)
3	8.21 (17.4)	1.84 (4.3)	5.62 (12.1)
4	8.49 (17.3)	1.80 (4.3)	5.85 (12.1)
5	7.90 (16.6)	1.16 (3.9)	5.92 (11.7)
p-value for linear trend	<0.001	<0.001	<0.001

^*All analyses adjusted for age, gender, BMI, baseline radiographic severity, and time between baseline and follow-up assessments

^†Negative WOMAC change scores indicate improved symptoms and function; positive scores indicate worse symptoms and function.