Fig. 3.
Roles for the BLM dissolvasome in HR-dependent DSB repair. Shown here is the pathway for DSB repair, showing the different steps where BLM and/or the BLM dissolvasome may act or stimulate. The pathways shown here are resolved to non-crossover products, either via synthesis-dependent strand annealing (SDSA) (left) or dHJ dissolution (right); however, the dHJ substrate may also be resolved via HJ resolvases as shown in Fig. 2. New DNA synthesis is depicted with a dashed line