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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Nitric Oxide. 2012 Jul 20;27(4):201–209. doi: 10.1016/j.niox.2012.07.002

Figure 2. Copper specifically reduces nitrite in LPS-challenged BV2 microglia.

Figure 2

Nitrite reduction is specific to Cu(I) and it is not observed with the non-redox active metals. BV2 microglia were challenged with 100 μM CuCl [Cu(I)], CuCl2 [Cu(II)], ZnCl2 and MgCl2 for 8 hrs prior to stimulation with 1000 ng/mL LPS. Data are Mean ± S.E. of duplicate cultures, representative of 2 independent experiments. * LPS 1000 vs. LPS 1000 + Cu(I) 100 μM indicates p < 0.05.