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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Br J Dermatol. 2013 Aug;169(2):406–411. doi: 10.1111/bjd.12313

Table 1.

Known psoriasis susceptibility loci of genome wide significance.

No. Chr. Position* (Mb) Nearby Gene(s) Population Reference
1 1 8.27 SLC45A1, TNFRSF9 Caucasian 12
2 1 24.52 IL28RA Caucasian 9
3 1 25.29 RUNX3 Caucasian 12
4 1 67.73 IL23R Caucasian 4
5 1 152.59 LCE deletion Caucasian, Chinese 6, 5
6 2 61.08 REL Caucasian 9
7 2 62.55 B3GNT2 Caucasian 12
8 2 163.26 IFIH1 Caucasian 9
9 5 15.99 PTTG1 Chinese 8
10 5 96.12 ERAP1 Caucasian, Chinese 9, 8
11 5 132.00 IL13/IL4 Caucasian 4
12 5 150.47 TNIP1 Caucasian, Chinese 4, 8
13 5 158.83 IL12B Caucasian, Chinese 4,5
14 6 0.58 EXOC2/IRF4 Caucasian 12
15 6 31.26 HLA-C Caucasian, Chinese 4
16 6 111.91 TRAF3IP2 Caucasian 9,10
17 6 138.20 TNFAIP3 Caucasian 4
18 6 159.51 TAGAP Caucasian 12
19 7 37.39 ELMO1 Caucasian 12
20 8 3.68 CSMD1 Chinese 8
21 9 32.52 DDX58 Caucasian 12
22 9 110.82 KLF4 Caucasian 12
23 10 81.03 ZMIZ1 Caucasian 11
24 11 64.14 PRDX5 Caucasian 11
25 11 109.96 ZC3H12C Caucasian 12
26 11 128.41 ETS1 Caucasian 12
27 12 56.75 IL23A/STAT2 Caucasian 4
28 13 20.76 GJB2 Chinese 8
29 14 35.83 NFKBIA Caucasian 7
30 16 11.37 SOCS1 Caucasian 12
31 16 31.00 FBXL19 Caucasian 7
32 17 26.12 NOS2 Caucasian 7
33 17 40.56 STAT3, STAT5A/B Caucasian 12
34 17 78.18 CARD14 Caucasian 12
35 18 61.66 SERPINB8 Chinese 8
36 18 51.82 STARD6, POLI, MBD2 Caucasian 12
37 19 53.45 ZNF816A Chinese 8
38 19 10.46 TYK2 Caucasian 9
39 19 10.82 ILF3, CARM1 Caucasian 12
40 20 48.56 RNF114 Caucasian 3
41 22 21.98 UBE2L3 Caucasian 11
*

Positions refer to hg19/GRCh37 (http://genome.ucsc.edu)