Table 1.
NP1 | NP2 | NP3 | NP4 | NP5 | NP6 | NP7 | NP8 | NP9 | CP1 | CP2 | CP3 | CP4 | CP5 | CP6 | CP7 | CP8 | CP9 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gender | male | male | male | female | female | female | male | female | male | male | female | male | female | male | male | female | female | female |
Age (years) | 55 | 53 | 48 | 30 | 32 | 30 | 23 | 55 | 56 | 42 | 44 | 41 | 49 | 58 | 68 | 64 | 61 | 53 |
Race | white | white | white | white | white | white | white | white | hispanic | white | white | hispanic | white | white | white | white | white | white |
Smoker | − | + | + | − | − | − | − | − | − | − | + | + | + | + | + | + | − | + |
Alcohol | + | − | + | − | − | − | − | − | − | − | − | + | + | − | + | + | − | + |
TIGAR-O | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | G | G | T | T | I | T | T | I | T |
Symptoms | pain | pain | pain, weight loss |
pain, diarrhea |
pain | pain | pain | diarrhea | pain | pain, re- current pancreatitis |
pain, re- current pancreatitis |
pain | pain | pain | pain | none | weight loss, pain |
pain |
CT Scan Findings |
none | none | none | none | none | none | none | none | none | calcifi- cation |
calcifi- cation dilated main duct |
calcifi- cation |
n/a | calcifi- cation |
calcifi- cation dilated main duct, atrophy |
dilated duct, calcifi- cation atrophy |
calcif- cation, dilated duct, atrophy |
calcifi- cation cyst |
CT Grade | normal | n/a | normal | n/a | normal | n/a | normal | normal | normal | definite | definite | definite | n/a | definite | definite | definite | definite | definite |
EUS Score | 1 | 4 | 2 | n/a | 4 | 2 | 3 | 1 | n/a | 5 | 5 | n/a | 7 | n/a | 5 | n/a | 8 | 6 |
MRI grade | n/a | 0 | n/a | 0 | 0 | 0 | 0 | 0 | 0 | IV | IV | IV | III | IV | IV | IV | IV | IV |
CP based on imaging |
− | − | − | − | − | − | − | − | − | + | + | + | + | + | + | + | + | + |
Peak [HCO3−] |
80 | 84 | 101 | 115 | 81 | 90 | 84 | 92 | 114 | 60 | 26 | 22 | 41 | 22 | 39 | 37 | 54 | 38 |
Secretory dysfunction |
− | − | − | − | − | − | − | − | − | + | + | + | + | + | + | + | + | + |
TIGAR-O: T, Toxic-metabolic; I, Idiopathic; G, Genetic; A, Autoimmune; R, Recurrent and severe acute pancreatitis; O, Obstructive. EUS scores: 0–2 is normal, 3–4 is equivocal, >5 is definite CP. MRI/MRCP Grade (Cambridge classification: normal=0, equivocal=I, mild=II, moderate=III, severe=IV). Secretory dysfunction: yes (+) <80, no (−) ≥80. n/a, not available.