Table 5.
Comparison of modifications across all sample types. The following ten modifications were identified with statistically different frequencies in the non-pancreatitis verses chronic pancreatitis pancreatic fluid samples.
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|---|---|---|---|---|---|---|
| Frequency of modification per 1,000 potential modification sites | ||||||
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| Modification | PF | Bile | Urine | GDF | PaSC | PaDC |
| Acetyl(N-term) | 11.13 | 16.02 | 24.80 | 8.53 | 1.97 | 41.01 |
| Carbamyl(N-term) | 3.57 | 3.61 | 0.70 | 3.01 | 0.66 | 1.43 |
| Cation:K(D) | 1.67 | 1.07 | 0.11 | 0.00 | 0.74 | 0.18 |
| Cation:Na(D) | 0.37 | 0.10 | 0.11 | 0.84 | 0.25 | 0.00 |
| Deamidated(Q) | 127.29 | 101.69 | 23.89 | 66.24 | 17.60 | 14.50 |
| Dehydrated(E) | 0.35 | 0.00 | 0.06 | 1.94 | 0.00 | 0.00 |
| Gln->pyro-Glu(N-term) | 297.88 | 410.20 | 454.55 | 451.61 | 298.25 | 363.82 |
| Nitro(W) | 0.29 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Oxidation(M) | 589.72 | 264.02 | 391.73 | 870.37 | 714.29 | 844.93 |
| Oxidation(P) | 12.35 | 6.39 | 20.34 | 4.84 | 19.42 | 13.38 |
PF, pancreatic fluid; GDF, gastroduodenal fluid; PaSC, pancreatic stellate cells; PaDC, pancreatic duct cells.