Table 6.
The modifications with the highest frequency comparing pancreatic fluid (PF), bile, gastroduodenal fluid (GDF), urine, pancreatic stellate cells (PaSC), and pancreatic duct cells (PaDC).
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|
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|---|---|---|---|---|---|---|
| Frequency of modification per 1,000 potential modification sites | ||||||
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| ||||||
| Modification | PF | Bile | Urine | GDF | PaSC | PaDC |
| Acetyl(N-term) | 10.65 | 16.02 | 8.53 | 24.80 | 1.97 | 41.01 |
| Deamidated(N) | 208.86 | 170.25 | 135.72 | 101.60 | 48.53 | 62.41 |
| Deamidated(Q) | 126.98 | 101.69 | 66.24 | 23.89 | 17.60 | 14.50 |
| Deamidated(R) | 35.34 | 21.37 | 7.85 | 6.39 | 11.92 | 5.68 |
| Delta:H(2)C(2)(H) | 10.02 | 11.42 | 15.92 | 18.87 | 9.51 | 7.90 |
| Dioxidation(M) | 14.35 | 2.16 | 7.41 | 10.18 | 2.72 | 15.19 |
| Dioxidation(W) | 21.60 | 13.09 | 0.00 | 29.89 | 53.94 | 7.76 |
| Gln->pyro-Glu(N-term) | 309.07 | 410.20 | 451.61 | 454.55 | 298.25 | 363.82 |
| Glu->pyro-Glu(N-term) | 30.12 | 31.89 | 27.03 | 39.04 | 4.72 | 5.55 |
| Oxidation(H) | 18.31 | 6.48 | 19.11 | 14.07 | 5.95 | 4.65 |
| Oxidation(M) | 591.25 | 264.02 | 870.37 | 391.73 | 714.29 | 844.93 |
| Oxidation(P) | 12.54 | 6.39 | 4.84 | 20.34 | 19.42 | 13.38 |
| Oxidation(W) | 27.05 | 10.29 | 37.88 | 29.41 | 16.60 | 7.76 |
| Protein Terminal Acetyl(N-term) | 17.76 | 65.60 | 0.00 | 0.00 | 321.31 | 568.03 |