Table 3.
Variables associated with mortality
| (N=60 cases) | Alive at discharge (N=34; 57%) | Deceased (N=26; 43%) | p-value (univ.) | p-value (multiv.) | OR (multiv.) |
|---|---|---|---|---|---|
| Duration of ketamine; days; median (range) | 4 (0–24) | 4 (0–27) | NS | - | - |
| Dose of ketamine; mg/kg/h; median (range) | 1.7 (0.05–10) | 3.6 (0–10) | NS | - | - |
| Response to ketamine (N=19); N (row %) | 16 (84%) | 3 (16%) | 0.0014 | 0.001 | 0.007–0.3 |
| Age; years; median (range) | 26 (7mo–85) | 51 (19–76) | 0.0025 | <0.001 | 1.02–1.1/year |
| Etiology | 0.0127 | NS | - | ||
| Unknown (N=34); N (row %) | 18 (53%) | 16 (47%) | |||
| Anoxic (N=7); N (row %) | 2 (29%) | 5 (71%) | |||
| Acute non anoxic (N=13); N (row %) | 9 (69%) | 4 (31%) | |||
| Remote (N=6); N (row %) | 5 (83%) | 1 (17%) | |||
| Status classification | NS | - | - | ||
| Generalized convulsive (N=14); N (row %) | 8 (56%) | 6 (44%) | |||
| Generalized nonconvulsive (N=3); (row %) | 1 (33%) | 2 (67%) | |||
| Focal convulsive (N=4); N (row %) | 2 (50%) | 2 (50%) | |||
| Focal nonconvulsive (N=38); N (row %) | 25 (66%) | 13 (33%) | |||
| Status epilepticus of infantile spasms; N (row %) | 1 (100%) | 0 (0%) | |||
| Any adverse event (N=18); N (row %) | 8 (44) | 10 (66%) | NS | - | - |
| Concurrent anesthetic drugs*; median (range) | 2 (0–3) | 2 (1–3) | NS | - | - |
Abbreviations: univ. = univariate analysis; multiv. = multivariate analysis;;
anesthetic drugs include pentobarbital, thiopental, midazolam and propofol.