Figure 2.
Synthesis of A1443 and [3H]A1443. (a) 4 N HCl/dioxane. (b) N,N-diisopropylethylamine (DIEA), 1-(3-dimethylaminopropyl) -3-ethylcarbodiimide (EDCI), 4-dimethylaminopyridine (DMAP). (c) 10% Pd/C, H2 or 3H2, EtOH.
Synthesis of A1443 and [3H]A1443. (a) 4 N HCl/dioxane. (b) N,N-diisopropylethylamine (DIEA), 1-(3-dimethylaminopropyl) -3-ethylcarbodiimide (EDCI), 4-dimethylaminopyridine (DMAP). (c) 10% Pd/C, H2 or 3H2, EtOH.