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Detection of anti-ICAM-1 antibodies in serum from SSc patients. Levels of anti-ICAM-1 IgG and IgM antibodies were measured in serum from 60 patients with scleroderma (n = 32 LSSc, n = 28 DSSc) and from 26 healthy controls, using immobilised recombinant human ICAM-1 as the capture antigen. *p < 0.05; **p < 0.01, Mann–Whitney tests compared to healthy controls.
