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. 2013 Mar 13;84(2):297–307. doi: 10.1038/ki.2013.81

Figure 2.

Figure 2

Mesenchymal stem cells (MSCs) suppressed α-smooth muscle actin (α-SMA) and fibroblast-specific protein-1 (FSP-1) expressions in rats with peritoneal fibrosis. Immunohistochemical analyses of (a) α-SMA and (b) FSP-1 expression in peritoneal tissues on days 7 and 14 (original magnification × 200) in control rats, chlorhexidine gluconate (CG)-injected rats treated with the vehicle alone, and CG-injected rats treated with MSCs. (c, d) Accumulation of α-SMA+ and FSP-1+ cells was observed on days 7 and 14 in CG-injected rats treated with the vehicle, whereas the areas (percentage) of α-SMA expression and the number of FSP-1+ cells were significantly smaller on both days 7 and 14 in CG-injected rats treated with MSCs. *P<0.01 versus control group, #P<0.05 versus CG+vehicle group.