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Parameters (EC50 and h) obtained from the Hill–Langmuir fit of TMEM16A, TMEM16B, TMEM16A-B and TMEM16B-A [Ca2+]i– response relationships
| TMEM16A | TMEM16A-B | TMEM16B | TMEM16B-A | |
|---|---|---|---|---|
| EC50 (μm) | 1302 ± 33† | 1304 ± 69† | 1860 ± 53* | 881 ± 40*,† |
| (n= 5) | (n= 6) | (n= 6) | (n= 6) | |
| h | 2.7 ± 0.1 | 2.7 ± 0.2 | 2.8 ± 0.1 | 2.5 ± 0.1 |
| (n= 5) | (n= 6) | (n= 6) | (n= 6) |
and † indicate statistically significant difference from TMEM16A and TMEM16B, respectively.
