Table 2.

Positive and Negative Regulators of Expression of Genes Coding for (hemi)cellulolytic Enzymes and Their Binding consensus Sequences in the Target Promoters

Trichoderma reesei
Positive Regulators
Name	Structure	Consensus Region	References
XYR1	Zinc binuclear cluster protein	5’-GGCTAA	[194] [25]
ACE2	Zinc binuclear cluster proteins	5ʹGGCTAATAA
HAP2	Multimeric protein complex	5’- CCAAT
HAP3
HAP5
Negative regulators
Name	Structure	Consensus region	References
ACE1	Three Cys2His2-type zinc fingers	5’-AGGCA	[25] [195]
CRE1	Cys2His2 type transcription factor	5’-SYGGRG
Neurospora crassa
Positive regulators
Name	Structure	Consensus region	References
CLR-1/-2	Two zinc binuclear cluster	-	[145]
PacC	Three Cys2His2 zinc fingers	5’-GCCARG	[147]
Neurospora crassa
Positive regulators
Name	Structure	Consensus region	References
XLR1	Zinc binuclear cluster protein		[148]
NIT2	Single zinc finger protein	5’- TATCTA	[149]
Negative regulators
Name	Structure	Consensus region	References
CRE1	Cys2His2 type transcription factor	5’-SYGGRG-	[152]
Aspergillus spp.
Positive regulators
Name	Structure	Consensus region	References
AmyR	Zn(II)2Cys6-binuclear cluster DNA-binding motif	5’-CGGN8CGG-3'	[194,-196]
AraR	Zn(2)Cys(6) binuclear cluster domain		[197,198]
PacC	Three Cys2His2 zinc fingers	5’- GCCARG	[22]
XlnR	Zinc binuclear cluster protein	5'-GGCTAAA	[48]
ClbR	Zn(II)2Cys6-binuclear cluster DNA-binding motif	CGG or CCG triplets	[174]
AreA	Highly conserved DNA binding motif comprising a Cys(4) zinc finger followed by a basic domain	5’-GATA (core sequence)	[182]
Negative regulators
Name	Structure	Consensus region	References
CREA	Cys2His2 type transcription factor	5’-SYGGRG	[183-187]
CREB
CREC