Figure 1.

Participant flow diagram. CKD was defined by at least two measurements of eGFR <60 ml/min per 1.73 m² ≥90 days apart with no interceding values ≥60 ml/min per 1.73 m². Of these, we selected the subset whose last eGFR measurement was <15 ml/min per 1.73 m². For this subset, the date where eGFR was first <15 ml/min per 1.73 m² was considered as the index date for kidney failure. AKDN, Alberta Kidney Disease Network; SCr, serum creatinine; eGFR, estimated GFR; RRT, renal replacement therapy.