Table 1.
Demographic and clinical characteristics of participants with kidney failure
| Characteristic | Study Endpoint | P Valuea | ||
|---|---|---|---|---|
| Initiated Chronic RRT | Died | Censored | ||
| Participants | 1997 (25) | 3372 (43) | 2532 (32) | — |
| Follow-up (mo) | 7.2 (2.5, 16.3)b | 5.2 (0.9, 15.8) | 19.8 (8.4, 38.2) | — |
| Age (yr) | 65 (53, 74) | 83 (76, 89) | 76 (66, 83) | <0.001 |
| Male sex | 1198 (60) | 1429 (42.4) | 1066 (42.1) | <0.001 |
| Aboriginal | 140 (7) | 68 (2) | 53 (2.1) | <0.001 |
| Social assistance | 205 (10.3) | 54 (1.6) | 103 (4.1) | <0.001 |
| Rural | 322 (16.1) | 499 (14.8) | 394 (15.6) | 0.19 |
| Distance (km) | 20 (20, 60) | 20 (20, 80) | 20 (20, 80) | 0.002 |
| Comorbidities | ||||
| Diabetes | 1091 (54.6) | 1493 (44.3) | 1177 (46.5) | <0.001 |
| Hypertension | 1808 (90.5) | 2990 (88.7) | 2334 (92.2) | 0.03 |
| Charlson scorec | 4 (2, 6) | 5 (3, 7) | 4 (2, 5) | <0.001 |
| AIDS/HIV | 0 (0) | 1 (0) | 1 (0) | — |
| Cancer, metastatic | 36 (1.8) | 317 (9.4) | 72 (2.8) | <0.001 |
| Cancer, nonmetastatic | 261 (13.1) | 884 (26.2) | 407 (16.1) | <0.001 |
| Cerebrovascular disease | 228 (11.4) | 794 (23.5) | 341 (13.5) | <0.001 |
| Chronic obstructive lung disease | 517 (25.9) | 1410 (41.8) | 758 (29.9) | <0.001 |
| Dementia | 49 (2.5) | 988 (29.3) | 260 (10.3) | <0.001 |
| Heart failure | 587 (29.4) | 1992 (59.1) | 908 (35.9) | <0.001 |
| Mild liver disease | 79 (4) | 89 (2.6) | 82 (3.2) | 0.01 |
| Mod/severe liver disease | 19 (1) | 58 (1.7) | 20 (0.8) | 0.02 |
| Myocardial infarction | 338 (16.9) | 944 (28) | 454 (17.9) | <0.001 |
| Paralysis | 45 (2.3) | 112 (3.3) | 44 (1.7) | 0.03 |
| Peptic ulcer | 154 (7.7) | 305 (9) | 149 (5.9) | 0.09 |
| Peripheral vascular disease | 275 (13.8) | 621 (18.4) | 339 (13.4) | <0.001 |
| Rheumatologic disease | 89 (4.5) | 167 (5) | 122 (4.8) | 0.41 |
| Affective disorder | 391 (19.6) | 734 (21.8) | 584 (23.1) | 0.06 |
| Psychotic disorder | 49 (2.5) | 206 (6.1) | 90 (3.6) | <0.001 |
| Proteinuria | <0.001 | |||
| Heavy/severe | 1175 (58.8) | 803 (23.8) | 694 (27.4) | |
| None/mild/moderate | 518 (25.9) | 1960 (58.1) | 1657 (65.4) | |
| Not measured | 304 (15.2) | 609 (18.1) | 181 (7.1) | |
Data are presented as n (%) or median (interquartile range). RRT, renal replacement therapy.
a
Comparison of the group that initiated chronic dialysis with the group that died during follow-up.
b
If followed until end of study, death, or moving, then follow-up is 48.1 (29.6, 63.5).
c
Charlson score includes AIDS/HIV, metastatic cancers, nonmetastatic cancers, cerebrovascular disease, chronic obstructive lung disease, dementia, diabetes, heart failure, mild liver disease, moderate/severe liver disease, myocardial infarction, paraplegia, peptic ulcer, peripheral vascular disease, and rheumatologic disease. The median and interquartile range are presented.