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. 2013 Apr 11;8(8):1396–1405. doi: 10.2215/CJN.12931212

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Copyright © 2013 by the American Society of Nephrology

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Figure 4. — IL-17 production by ex vivo-expanded HD Tregs. (A and B) IL-17 and FOXP3 staining in freshly isolated Tregs from HCs and HD patients showing (A) representative and (B) cumulative data from five independent experiments. (C) IL-17 production from freshly isolated HC and HD Tregs is activated in the presence of inflammatory cytokines; cumulative data from five independent experiments are shown. (D and E) IL-17 staining in HC and HD Tregs expanded ex vivo in the presence or absence of Rapamycin, showing (D) representative and (E) cumulative data from five independent experiments. (F) IL-17 production from HC and HD Tregs expanded ex vivo in the presence or absence of Rapamycin, showing cumulative data from five independent experiments. *P<0.05.