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. Author manuscript; available in PMC: 2013 Aug 2.
Published in final edited form as: AJR Am J Roentgenol. 2008 Jul;191(1):115–123. doi: 10.2214/AJR.07.3550

TABLE 1.

Bone Marrow Burden Scoring Criteria: Signal Intensity

Lumbar Spine Femur
Intensity Points Intensity Points
STIR sequence STIR sequence
  Hyperintense 2   Hyperintense 2
  Slightly hyperintense 1   Slightly hyperintense 1
  Isointense 0   Isointense 0
  Slightly hypointense NA   Slightly hypointense NA
  Hypointense NA   Hypointense NA
  Mixed type 3
T1-weighted sequence T1-weighted sequence
  Slightly hyperintense 0   Slightly hyperintense or isointense 0
  Isointense 1   Slightly hypointense 1
  Slightly hypointense 2   Hypointense 2
  Hypointense 3

Note—Intensity is relative to subcutaneous fat, except for the lumbar spine T1-weighted sequence, which is relative to nondiseased intervertebral disk. N A = not applicable. Adapted with permission from Maas M, van Kujik C, Stoker J, et al. Quantification of bone involvement in Gaucher disease: MR imaging bone marrow burden score as an alternative to Dixon quantitative chemical shift MR imaging—initial experience. Radiology 2003;229:554–561 [16].