Table 3.
Grade 3 or 4 Toxicities During Chemotherapy and RIT
| Toxicity | R-CHOP |
RIT |
||||||
|---|---|---|---|---|---|---|---|---|
| Grade 3 |
Grade 4 |
Grade 3 |
Grade 4 |
|||||
| No. | % | No. | % | No. | % | No. | % | |
| Hemoglobin | 1 | 2 | ||||||
| Leukocytes | 8 | 14 | 10 | 18 | 9 | 17 | ||
| Lymphopenia | 11 | 19 | 6 | 11 | 18 | 35 | 4 | 8 |
| Neutrophils | 7 | 12 | 20 | 35 | 17 | 33 | 11 | 21 |
| Platelets | 1 | 2 | 2 | 4 | 8 | 15 | 16 | 31 |
| Fatigue | 1 | 2 | ||||||
| Diarrhea without previous colostomy | 2 | 4 | ||||||
| Muco/stomatitis (symptom), oral cavity | 1 | 2 | ||||||
| Febrile neutropenia | 2 | 4 | 1 | 2 | ||||
| Infection with grade 3-4 neutropenia, colon | 1 | 2 | ||||||
| Infection with grade 0-2 neutropenia, lung | 1 | 2 | ||||||
| Hypocalcemia | 1 | 2 | ||||||
| Hyperglycemia | 3 | 5 | 1 | 2 | ||||
| Hypoglycemia | 1 | 2 | ||||||
| Hyponatremia | 5 | 9 | ||||||
| Hyperuricemia | 1 | 2 | ||||||
| Neuropathy, sensory | 2 | 4 | ||||||
| Syncope | 1 | 2 | ||||||
| Dyspnea | 2 | 4 | ||||||
| Hypoxia | 1 | 2 | ||||||
| Worst degree | 18 | 32 | 22 | 39 | 21 | 40 | 20 | 38 |
Abbreviations: R-CHOP, rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone; RIT, radioimmunotherapy.