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CONSORT diagram illustrating patient flow on Southwest Oncology Group protocol S0016. AE, adverse event; CHOP-R, cyclophosphamide, doxorubicin, vincristine, prednisone chemotherapy with rituximab; CHOP-RIT, cyclophosphamide, doxorubicin, vincristine, prednisone chemotherapy followed by tositumomab/131I-tositumomab radioimmunotherapy.
