Table 1.
Characteristics of Patients Randomly Assigned on Southwest Oncology Group Protocol S0016
| Characteristic | CHOP-R (%) | CHOP-RIT (%) |
|---|---|---|
| Median age, years | ||
| CHOP-R | 54.5 | |
| CHOP-RIT | 53.3 | |
| Male sex | 53 | 55 |
| White race | 90 | 90 |
| Elevated β2M | 53 | 54 |
| B symptoms | 29 | 26 |
| Bulk > 10 cm | 24 | 26 |
| Hemoglobin < 12 gm/dL | 11 | 11 |
| BM involvement | 56 | 56 |
| Follicular grade 3 | 8 | 9 |
| Stage | ||
| II | 4 | 2 |
| III | 37 | 34 |
| IV | 59 | 64 |
| FLIPI risk | ||
| Low | 30 | 31 |
| Intermediate | 47 | 43 |
| High | 22 | 26 |
Abbreviations: BM, bone marrow; CHOP-R, cyclophosphamide, doxorubicin, vincristine, prednisone, and rituximab; CHOP-RIT, cyclophosphamide, doxorubicin, vincristine, prednisone with tositumomab/iodine I-131 tositumomab radioimmunotherapy; FLIPI, Follicular Lymphoma International Prognostic Index.