Appendix Table 1.

Associations Between Current Weight and Body Mass Index and Overall, MSS, and MSI Endometrial Cancer, Adjusted for Current Weight and/or Weight at Age 20 Years, Alberta, Canada, 2002–2006

Variable	All Cases (n = 467) vs. Controls (n = 1,030)		MSS Cases (n = 337) vs. Controls		MSI Cases (n = 130) vs. Controls		P-heta
	ORb	95% CI	ORb	95% CI	ORb	95% CI
Current weight, kg
≤63.1	1.00		1.00		1.00
>63.1–71.5	0.72	0.48, 1.07	0.64	0.41, 1.00	1.01	0.50, 2.03	0.26
>71.5–81.8	0.93	0.62, 1.39	0.85	0.54, 1.32	1.2	0.61, 2.46	0.34
>81.8	1.23	0.74, 2.04	1.11	0.63, 1.94	1.66	0.72, 3.79	0.37
P-trend	0.37		0.63		0.24
Body mass indexc
<25	1.00		1.00		1.00
25–<30	0.88	0.62, 1.24	0.79	0.49, 1.07	1.55	0.81, 2.94	0.034
≥30	1.04	0.66, 1.64	0.80	0.48, 1.32	2.23	1.03, 4.79	0.014
P-trend	0.86		0.38		0.05

Abbreviations: CI, confidence interval; MSI, microsatellite-instable; MSS, microsatellite-stable; OR, odds ratio.

^a P value for heterogeneity between odds ratios for MSS and MSI, both compared with controls.

^b Odds ratios were adjusted for reference age (years; continuous), residence type (rural or urban), age at menarche (≤12 years or >12 years), menopausal status/hormone use (peri- or postmenopausal/never use, peri- or postmenopausal/use of estrogen only, peri- or postmenopausal/any use of estrogen plus progesterone, or peri- or postmenopausal/other menopausal hormone use or premenopausal hormone use), parity/age at first pregnancy (nulliparous, 1–2/≤25 years, 1–2/>25 years, >2/≤25 years, or >2/>25 years), hypertension (ever or never), and waist circumference (cm; continuous).

^c Weight (kg)/height (m)².